TÜBİTAK projects completed or ongoing in our department
| Team | Project Name | Project No | Year |
| Çoğulu, Özgür; Gündüz, Cumhur; Çankaya, Tufan; Özkınay, Ferda; Özkınay, Cihangir | Subtelomeric region screening in chromosomes in idiopathic mental retardation | TÜBİTAK SBAG Project 102S024 | 2004 |
| Tosun, Metiner; Akçalı, K. Can; Kosova, Buket; Eraç, Yasemin | The role of the transformational expression of the TRPC gene family in the aging process in the rat vascular smooth muscle | TÜBİTAK SBAG Project 103S176 | 2007 |
| Tosun, Metiner; Kosova, Buket; Eraç, Yasemin; Selli, Çiğdem | Control of capacitive calcium intake with pharmacological and molecular approaches in the development of vasospasm | TÜBİTAK SBAG Project 104S568 | 2007 |
| Kosova, Buket; Tezcanlı, Burçin; Eroğlu, Zuhal; Gündüz, Cumhur; Topçuoğlu, Nejat; Selvi, Nur; Biray, Çığır; Özel, Rukiye; Saydam, Güray; Şahin, Fahri |
Permanent suppression of STAT3, STAT5A and STAT5B expressions via antisense-oligonucleotides and SIRNA in leukemia cell lines and induction of apoptosis
|
TÜBİTAK SBAG Project 105S459 | 2008 |
| Özkınay, Ferda; Kurugöl, Zafer; Çoker, Mahmut; Çoğulu, Özgür; Gündüz, Cumhur; Pehlivan, Sacide; Akın, Haluk; Koturoğlu, Güldane; Onay, Hüseyin; Ekmekçi, Aslıhan; Aykut, Ayça; Biray, Çığır |
Expression of vitamin D receptor polymorphisms in breastfeeding mothers and babies in maternal hair stem cells, relationship of vitamin D levels in breast milk and baby serum
|
TÜBİTAK SBAG Project 106S048 | 2008 |
| Gündüz, Cumhur; Oktar, Nezih; Çoğulu, Özgür; Akalın, Taner; Dalbastı, Tayfun | Determination of epigenetic changes of tumor suppressor genes in diffuse and high-grade glial tumors by quantitative analysis of realtime online PCR-based methylated alleles | TÜBİTAK SBAG Project 107S364 | 2010 |
| Tosun , Metiner; Erdal , Ş. Esra; Kosova , Buket; Eraç , Yasemin | Investigation of the functional expression pattern of the TRPC gene family in carcinogenesis by post-transcriptional gene silencing | TÜBİTAK SBAG Project 108S072 | 2011 |
| Lambrecht, Fatma Yurt; Durkan, Kübra; Gündüz, Cumhur | Technetium-99m labeled bombesin-like peptide conjugation as tumor imaging agent; Preparation of HYNIC-litorin and in vitro evaluation | TÜBİTAK SBAG Project 108S200 | 2011 |
| Aktuğ, Hüseyin; Kosova, Buket; Uysal, Ayşegül; Yavaşoğlu, Altuğ; Çetintaş, Vildan Bozok | On the experimental rattus albinus diabetes model; Investigation of the effects of in vitro fertilization and early embryogenesis process on gap junction and adhesion proteins | TÜBİTAK SBAG Project 109S457 | 2012 |
| Cumhur Gündüz, Çığır Biray Avci, Cenk Can, Yavuz Dodurga, Hüsniye Sağlam, Burak Turna, Oktay Nazlı |
Investigation of the synergistic effect of paclitaxel and herbal agents and endemic plant extracts on cell cycle and apoptosis signal transduction pathways in prostate cancer cell lines |
TÜBİTAK SBAG Project 110S093 | 2012 |
| Yeniel, Ahmet Özgür; Ergenoğlu, Ahmet Mete; Zekioğlu, Osman; Selvi, Nur; Kaymaz, Burçin |
Expression of cellular prion protein (PrPc) and COMMD-1 in normal and cases with preeclampsia with or without intrauterine growth retardatio |
TÜBİTAK SBAG Project 111S272 | 2012 |
| Ahmet Özbilgin, Cumhur Gündüz | The Emergence of L. Donovani Sensu Lato and Its Spread in Europe: Molecular Typing, Population Genetic Analysis and Risk Management | TÜBİTAK SBAG Project 109S448 | 2013 |
| Tosun, Metiner; Kırmızıbayrak Ballar, Petek; Eraç, Yasemin; Kosova, Buket; Karakaya Selli, Çiğdem | Functional genomic analysis of the mirna-expression pattern associated with post-transcriptional control of TRPC ion channel genes in human primary aortic smooth muscle cells. | TÜBİTAK SBAG Project 110S096 | 2013 |
| Yusuf Özbel, Seray Töz, Doç. Hüsniye Kayalar, İ. Cüneyt Balcıoğlu, Doç. İpek Östan, Doç. Fadile Zeyrek, Yrd. Doç. Cenk Durmuşkahya, Hatice Ertabaklar, Doç. Özgür Kurt, Cumhur Gündüz | Türkiye'de Yerli Bitki Türlerinin İn vitro ve in vivo Anti-Leishmanial Etkisinin Araştırılması | TÜBİTAK SBAG Project 110S289 | 2013 |
| Alkan, Mehmet Ziya; Alpman, Asude; Avcı, Çığır Biray; Töz, Seray; Özbel, Yusuf; Sözmen, Eser; Gündüz, Cumhur | Genome analysis of Leishmania tropica that causes cutaneous leishmaniasis in Turkey | TÜBİTAK SBAG Project 110S406 | 2013 |
| Nır Selvi Günel | Investigation of Placental Expressions of Cellular Prion Protein (PrPc) and Copper Metabolism-Related Gene Cluster (COMMD1) in Preeclamptic, Intrauterine Development Limitation and Healthy Pregnant Placentae | TÜBİTAK SBAG Project 111S272 | 2013 |
| Yavuz Anacak, Nezahat Olacak, Sunde Yılmaz Süslüer, Emine Serra Kamer, Cumhur Gündüz, Murat Olukman | Evaluation of the Effect of Techniques of Intensity-modulated radiotherapy (IMRT) and Volumetric-modulated arc therapy (VMAT) on Life Response in Cell Lines with a New Radiobiological Modeling | TÜBİTAK SBAG Project 113S367 | 2013 |
| Kasım Ocakoğlu, Fatma Yurt Lambchti Cumhr Gündüz | Synthesis of Symmetric / Asymmetric Macrocyclic Structures and Comparison of Biological Potentials for Tumor Imaging and Photodynamic Therapy | TÜBİTAK KBAG Project 112T565 | 2014 |
| Ahmet Özbilgin, Cumhur Gündüz | Investigation of Differences in Leishmania Strains Isolated from Cutaneous Leishmaniasis Patients in Turkey by Genotypic and Proteomic Methods and Determination of Clinical Reflections in the Mouse Model | TÜBİTAK SBAG Project 111S179 | 2014 |
| Yavuz Dodurga, Çığır Biray Avcı | Investigation of Possible Effect Mechanism of Sulfide Molecule on URG4 / URGCP Gene, A New Oncogene in Human Neuroblastoma Cells (SHSY5Y) | TÜBİTAK SBAG Project 113S167 | 2014 |
| Ferzan Lermioğlu Erciyas, Çığır Biray Avcı, Cumhur Gündüz | In Vitro Investigation of the Effects of Cinnamomum Cassia and C. Zeylanicum Bark Extracts on Endogenous and H2O2 Induced Oxidative DNA Damage and Repair in Diabetes | TÜBİTAK SBAG Project 112S120 | 2015 |
| Yilmaz Süslüer Sunde,Özyazici Mine,Gündüz Cumhur,Kivçak Bijen,Fafal Tuğçe | Biosynthesis and characterization of Ag and Fe nanoparticles with asphodelus aestivus extract and investigation of antioxidant and antitumoral activities of Ag and Fe nanoparticles | TÜBİTAK SBAG Project 114S730 | 2016 |
| Nır Selvi Günel | Preparation of LHRH Receptor-targeted Peg-Pla-Pga Triblock cisplatin polymeric micelles for the treatment of ovarian cancer and in vitro / Ex vivo / In vitro investigations of oral use possibilities | TÜBİTAK SBAG Project 214S292 | 2016 |
| Biray Avci Çiğir,Gündüz Cumhur,Ercan Gülinnaz,Vatansever Hafize Seda | Investigation of Anti-cancer activity after cultivation of natural killer cells differentiating from Adenosis Tissue Based Mesenchymal Stem Cells with pancreatic cancer cells | TÜBİTAK SBAG Project 214S650 | 2016 |
| Metiner Tosun, Buket Kosova | Functional Genomic Analysis of Depot-Controlled Calcium Inlet in Phenotypic Differentiation of Huh-7 Human Hepatocellular Carcinoma Cell Lines | TÜBİTAK SBAG Project 113S399 | 2017 |
| Akif hakan Kurt, Vildan Bozok Çetintaş | Investigation of Proliferative and Apoptotic Effects of G Protein Coupled Estrogen Receptor 1 (GPER1) in Gastrointestinal Adenocarcinoma Cells | TÜBİTAK SBAG Project 113S912 | 2017 |
| İnce Ocakoğlu Mine,Gündüz Cumhur,Yurt Onaran Fatma,Ocakoğlu Kasim,Biray Avci Çiğir | Synthesis Characterization of Nanocarriers Containing Phthalocyanine Derivatives and Investigation of In Vitro Photodynamic Therapy and Tumor Imaging Activity | TÜBİTAK SBAG Project 114Z430 | 2017 |
| Vildan Bozok Çetintaş | Development of shRNA Carrier Cellular Originated Exosome Formulations for Use in Anticancer Purposes | TÜBİTAK SBAG Project 115S829 | 2017 |
| Serin Sengel Süheyla,Köse Şükran,Biray Avci Çiğir,Yilmaz Süslüer Sunde,Gündüz Cumhur | Investigation of Long Non-Coding RNA Expression in Hepatitis B Patients | TÜBİTAK SBAG Project 214S225 | 2017 |
| Nır Selvi Günel | he effect of propolis on reducing allergic molecule content, antioxidant / anti-inflammatory activity and induction of apoptosis by biotechnological transformation | TÜBİTAK KBAG Project 116Z223 | Continues |
| Nır Selvi Günel | A new nanotechnological approach with Solid Lipid carriers for Glioblastoma Treatment | TÜBİTAK SBAG Project | Continues |
| Yusuf, Özbel, Ahmet Özbilgin, Cumhur Gündüz |
Parasitological, Molecular and Geographical Epidemiological Approach in Control of Cutaneous Leishmaniasis in Turkey
|
TÜBİTAK SBAG Project 114S999 | Continues |
| Cumhuır Gündüz | nvestigation of Cancer Stem Cell Differentiation by miRNA Effect in the Embryonic Reprogramming Process | TÜBİTAK SBAG Project 115S404 | Continues |
| Vildan Bozok Çetintaş | Development and In vitro Assessment of Monoclonal Antibody Coated miRNA / pDNA Carrier Solid Lipid Nanoparticle Actively Targeting EGFR Receptors of Cancer Cells | TÜBİTAK SBAG Project 115S566 | Continues |
| Özlem Göksel, Cumhuır Gündüz | Determination of Molecular Asthma Endotypes Through Exhaled breath Volatile Organic Compounds and Peripheral Blood MicroRNA Biomarkers (Voc / miRNA-Endotype) | TÜBİTAK SBAG Project 116S196 | Continues |
| Vildan Bozok Çetintaş | Development of Ultrasound Sensitive Nanobubble Formulations Carrying Paclitaxel, Survivin Inhibitor and siRNA Against Lung Cancer | TÜBİTAK SBAG Project 116S213 | Continues |
| Bilge Melek Duygu,Yilmaz Süslüer Sunde,Bilge Metin,Anacak Yavuz,Gündüz Cumhur,Kamer Emine Serra,Parlak Cemal,Yalman Deniz | Determination of Anticancer Characteristics of Tumor Treating Fields (TTF) and External Radiotherapy in Glioblastoma, Brain Cancer Stem Cell, Brain Stem Cell and Brain Endothelial Cell Lines | TÜBİTAK SBAG Project 117S070 | Continues |
| Vildan Bozok Çetintaş | Molecular Methods Investigation of Reciprocal Relationships between Cyclopamine Inhibition and Sonic Hedgehog Signal Path and Associated Autophagy, Apoptosis, Cell Cycle, Cell Skeleton, Hypoxia Mechanisms in Glioblastoma Multiforme and Glioblastoma Multiforme Cancer Stem Cells with Astrocyte Co-Cultures | TÜBİTAK SBAG Project 117S578 | Continues |
| Nır Selvi Günel | Gastroesophageal reflux and diabetes mellitus relationship; Investigation of the changes caused by diabetes in human esophageal epithelial integrity and tissue permeability using in vitro mini-ussing circle system and determination of molecular markers involved in physiopathological processes | TÜBİTAK SBAG Project 117S769 | Continues |
| Ali Saffet Gönül, Buket Kosova | Comparison of Neural Components Associated with Default Mode, Short Term Memory Recording and Recall of Individuals Diagnosed with Mild Cognitive Impairment with Early Alzheimer's Patients and Their Healthy Siblings and Controls | TÜBİTAK SBAG Project 214S029 | Continues |
| Ahmet Özbilgin, Cumhur Gündüz | Determination of the Molecular Mechanism of Gene Expression Regulation Responsible for Antimony Resistance Development in Leishmania Tropica | TÜBİTAK SBAG Project214S239 | Continues |
| Tuncay Göksel, Özlem Göksel, Cumhuır Gündüz | The Use of Liquid and Volatile Biopsy in Individual-Specific Molecular Diagnosis and Follow-up of Patients with Lung Cancer | TÜBİTAK SBAG Project216S591 | Continues |
