Doctoral Theses completed in our department
| Phd Std | THESIS TITLE | SUPERVISOR | YEAR | |||
| Mehmet Ali Kuru | Experimental Investigation of the Effects of Electrically Heated Tablet Preparations Used Against Mosquitoes on Respiratory System Cells of Inbred Mice | Prof. Dr. Nejat Topçuoğlu | 1991 | |||
| Berna Yılmaz | Demonstration of Intermediary Filaments in Central Nervous System Tumor Cells by Immunofluorescence Method | Prof. Dr. M. Ali Özcel | 1991 | |||
| Zuhal Balım | Comparison of DNA Values with Micro Spectrophotometric Measurements in Normal Proximal Tube Epithelium and Kidney Adenocarcinoma Cells | Prof. Dr. Nejat Topçuoğlu | 1991 | |||
| Gül Sapmaz | Karyotype and BrDU Research in Mothers with Toxoplasmosis | Prof. Dr. Cihangir Özkınay | 1992 | |||
| Nuray Altıntaş | Investigation of the Protozoans Living in the Digestive System of the Aegean Region Termites and Investigation of Their Similarities with the Human Digestive System Protozoans | Prof. Dr. M. Ali Özcel | 1994 | |||
| Cumhur Gündüz | Comparative Investigation of Chorionic Villus Karyotype with Material Blood Fetal Karyotype in Medical Abortion | Prof. Dr. Cihangir Özkınay | 1994 | |||
| Berrin Tuğrul | Investigation of Factor V Leiden and Prothrombin 20210A Mutations in Patients with Deep Vein Thrombosis and Factor V Leiden Analysis with Electrochemical DNA Biosensors | Prof. Dr. Nejat Topçuoğlu | 2003 | |||
| Nur Selvi | Investigation of t(8;14), t(14;18) Chromosomal Rearrangements in Paraffin Sections of Patients Diagnosed with Burkitt Lymphoma and Follicular Lymphoma Polymerase Chain Reaction | Prof. Dr. Nejat Topçuoğlu | 2009 | |||
| Çığır Biray Avcı | The Importance of Tumor Suppressor Genes and Oncogenes in the Diagnosis and Prognosis of Anaplastic Brain Tumors | Assoc. Prof. Dr.Cumhur Gündüz | 2009 | |||
| Yavuz Dodurga | Investigation of the Correlation of URG4 with Gene Expression in Signal Transduction Pathways in Leukemogenesis | Prof. Dr. Nejat Topçuoğlu | 2010 | |||
| Burçin Kaymaz | Suppression of STAT3, STAT5A and STAT5B Expressions in K562 Leukemia Cell Line with Modified siRNAs and Induction of Apoptosis | Asist. Prof. Dr. Buket Kosova | 2010 | |||
| Vildan Bozok Çetintaş | Effects of 14-3-3 sigma expression and methylation levels in the development of chemotherapy resistance in non-small cell lung cancer cell series | Prof. Dr. Nejat Topçuoğlu | 2011 | |||
| Aslı Tetik Vardarlı | Determination of Genomic Profiles of Primary and Diabetic Dyslipidemia in Cardiovascular Diseases | Assoc. Prof. Dr. Zuhal Eroğlu | 2011 | |||
| Zeynep Özlem Doğan Şığva | Investigation of the synergistic effect of paclitaxel with herbal agents and endemic plant extracts on cell cycle and apoptosis signal transduction pathways in prostate cancer cell lines | Prof. Dr. Cumhur Gündüz | 2012 | |||
| Sunde Yılmaz Süslüer | Determination of miRNA expression changes in diffuse and high-grade glial tumors | Prof. Dr. Cumhur Gündüz | 2012 | |||
| Çağdaş Aktan | Determination of miRNA Targeting Androgen Receptor and Investigation of Developing Resistance Mechanism on Androgen Sensitive and Castration-Resistant Prostate Cancer Cell Series | Assoc. Prof. Dr. Buket Kosova | 2013 | |||
| Ayşegül Dalmızrak | Determination of the Effects of the Chemotherapeutic Agent “Rituximab” on JAK-STAT and NF-KB Signal Pathways in Acute Lymphoblastic Leukemia and Chronic Lymphocytic Leukemia Cell Lines | Assoc. Prof. Dr. Buket Kosova | 2014 | |||
| Duygu Aygüneş | The Effect of Using Trastuzumab, Docetaxel and Fucoidan as Single Agents and Combined Agents on Breast Cancer Cell Lines on Apoptosis and Cell Toxicity | Assoc. Prof. Dr. Buket Kosova | 2014 | |||
| Tuğçe Balcı | Investigation of Functions of Long-nonCoding RNAs in Brain Tumors | Prof. Dr. Cumhur Gündüz | 2015 | |||
| Ali Şahin Küçükaslan | Investigation of the Relationship Between SIRT1 Gene Expression and MiRNAs Targeting SIRT1 in H9c2 Cell Series Exposed to High Dose Glucose | Assoc. Prof. Dr. Zuhal Eroğlu | 2016 | |||
| Çağla Kayabaşı | Effects of Ponatinib and Vs-5584 Therapeutic Agents on Chronic Myeloid Leukemia Leukemogenesis | Prof. Dr. Cumhur Gündüz | 2018 | |||
| Besra Özmen Yelken | In Vitro Evaluation of Anti-Cancer Effectiveness of Resveratrol Analogue in Prostate Cancer Cells | Prof. Dr. Cumhur Gündüz | 2018 | |||
| Zeynep Mutlu | Molecular Investigation of Long-nonCoding RNA Expression in Patients with Chronic Myeloid Leukemia Sensitive and Resistant to Tyrosine Kinase Inhibitors |
Assoc. Prof. Dr. Çığır Biray Avcı Assoc. Prof. Dr. Archa Fox |
2018 | |||
| Nevin Oruç | The Importance of lncRNAs in the Diagnosis and Prognosis of Pancreatic Cancer | Assoc. Prof. Dr. Zuhal Eroğlu | 2019 | |||
| Meltem Seziş Demirci | Investigation of Different Expression Profiles of the "Transient Receptor Potential Ion Channel (TRPC) Gene Family" in Patients Undergoing Kidney Biopsy with Clinically Suspected Glomerulonephritis | Assoc. Prof. Dr. Buket Kosova | 2019 | |||
| İpek Kaplan Bulut | Evaluation of suPAR and SIRT1 as cardiovascular markers in pediatric patients with chronic renal failure. | Assoc. Prof. Dr. Buket Kosova | 2019 | |||
| Metin Çalışkan | Investigation of Oncogene Changes After First-line Treatment in Patients with Lung Adenocarcinoma from Peripheral Blood Free DNA (cfDNA) Samples | Assoc. Prof. Dr. Nur Selvi Günel | 2019 | |||
| Ahmet Çağ Çal | Effect of zoledronic acid treatment on cell adhesion molecules in prostate cancer stem cells | Prof. Dr. Cumhur Gündüz | 2019 | |||
| Sezgi Kıpçak | Determination of epithelial molecules playing a role in the etiopathogenesis of achalasia and examination of epithelial permeability | Assoc. Prof. Dr. Nur Selvi Günel | 2021 | |||
| Bakiye Göker | Determination of genomic profile that may constitute a treatment target in paranasal sinus carcinogenesis | Assoc. Prof. Dr. Çığır Biray Avcı | 2021 | |||
| Hale Güler Kara | Identification of genetic factors involved in the development of cisplatin resistance in non-small cell lung cancer using CRISPR-CAS9 based whole genome screening system | Doç.Dr. Buket Kosova | 2021 | |||
| Neslihan Pınar Özateş | Investigation of the effect of inhibition of the Hippo signaling pathway effector molecule YAP1 on brain cancer and brain cancer stem cells in vitro | Assoc. Prof. Dr. Çığır Biray Avcı | 2021 | |||
| Aycan Aşık | Investigation of genetic factors in the molecular pathogenesis of Hereditary Angioedema without SERPING1 mutation | Prof. Dr. Cumhur Gündüz | 2022 | |||
| Aygül Çeltik | Evaluation of the association between two important diabetes complications and Nrf2 gene polymorphism | Assoc. Prof. Dr. Fatma Zuhal Eroğlu | 2022 | |||
| Cansu Çalışkan Kurt | Investigation of the effects of the combination of maslinic acid and oleanolic acid on the WNT signaling pathway in breast cancer at the molecular level | Assoc. Prof. Dr. Çığır Biray Avcı | 2022 | |||
| Buket Özel | Development of polymer drug nanoconjugate for use in ovarian cancer and investigation of its cancer treatment potential | Assoc. Prof. Dr. Nur Selvi Günel | 2022 | |||
| Ahmet Keskinoğlu | Effect of endoplasmic reticulum stress on graft functions in the presence of hypertension in pediatric kidney transplant patients |
Assoc. Prof. Dr. Fatma Zuhal Eroğlu Prof. Dr. Muhsin Özgür Çoğulu |
2023 | |||
| Latife Merve Oktay Çelebi | Investigation of the effects and bioactivity of cnisin in combination with conventional chemotherapeutic agents on molecules on cancer-related signaling pathway | Assoc. Prof. Dr. Nur Selvi Günel | 2023 | |||
| Fatma Söğütlü | Epigenetic evaluation of the anticancer role of oregano oil in gastric cancer | Assoc. Prof. Dr. Çığır Biray Avcı | 2023 | |||
| Mesude Angın | Somatic mutation analysis for BRAF, NRAS, TERT, TP53 genes in Anaplastic Thyroid Cancer | Prof. Dr. Emin Karaca | 2024 | |||
| Fazilet Esra Düzdağ | Investigation of the effectiveness of combined use of epigenetic agents and adjuvant immunotherapy in the conventional treatment of triple negative breast cancer | Assoc. Prof. Dr. Burçin Kaymaz | 2024 | |||
| Roya Gasımlı | Investigation of the effects of silencing mitochondrial mutant gene expressions on carcinogenesis in a lung cancer cell mode | Prof. Dr. Cumhur Gündüz | 2024 | |||
| Eda Doğan | Effects of endoplasmic reticulum-Golgi vesicular traffic on sting activation | Assoc. Prof. Dr. Vildan Bozok Çetintaş | 2024 | |||
| Özlem Göksel | Investigating the roles of circular RNAs in different asthma severity levels | Prof. Dr. Cumhur Gündüz | 2024 | |||
| İbrahim Halil Çitçi | Effects of TCF7L2 on nicotine dependence and glucose metabolism in nicotine-dependent rat strains. | Prof. Dr. Buket Kosova | 2024 | |||
| Semahat Çelikten | Effect of thapsigargin on ER stress and cisplatin resistance in cisplatin-resistant Calu 1 and H030 non-small cell lung cancer cell lines | Prof. Dr. Vildan Bozok | 2025 | |||
| Deniz Bolat | Investigation of urinary cyclic RNAs as a potential biomarker in the diagnosis of bladder cancer. | Assoc. Prof. Dr. Burçin Kaymaz | 2025 | |||
| Selahattin Alperen Uysal | Identifying new drug targets for Alzheimer's disease treatment through gene expression analysis data | Assoc. Prof. Dr. Burçin Kaymaz | 2025 | |||
| Umut Öztürk | Investigation of the relationship between specific miRNAs and the expression of E-cadherin and vimentin in exhaled condensate samples from patients with non-small cell lung cancer | Assoc. Prof. Dr. Aslı Tetik Vardarlı | 2025 | |||
| İsmail Mert Alkaç | Improving the efficacy of treatment in breast cancer by silencing genes that confer resistance to CDK inhibitors using miRNA silencing | Prof. Dr. Çığır Biray Avcı | 2025 | |||
| Sanem Keskin Yılmaz | A Novel Method in the Diagnostic Algorithm of Developmental and Epileptic Encephalopathies of Undetermined Genetic Cause: Optical Genome Mapping | Assoc. Prof. Dr. Nur Selvi Günel | 2025 | |||
| Leıla Sabour Takanlou | Investigation of the Potential of EZH2 Inhibitor Tazemetostat as an Alternative Treatment Target in Gastric Cancer | Prof. Dr. Çığır Biray Avcı | 2025 |
