Master's Theses
This page presents the master's theses prepared within the department in a structured archive format, including author, thesis title, supervisor and year information.
| Author | Thesis Title | Supervisor | Year |
|---|---|---|---|
| Cumhur Gündüz | Effects of dust retained in chimney filters of a cement factory on alveolar macrophages of experimentally dust-exposed white mice | Doç. Dr. Nejat Topçuoğlu | 1984 |
| Berna Aksakal | Investigation of protozoan cysts and helminth eggs carried by houseflies on their legs | Prof. Dr. M. Ali Özcel | 1984 |
| Gül Sapmaz | Comparative examination of Trichomonas vaginalis (Donne, 1836) obtained from culture using various staining methods | Doç. Dr. Seza Budak | 1984 |
| Gürcan Güleryüz | Studies on the effects of linear alkylbenzene sodium sulfonate on Paramecium sp. | Doç. Dr. Seza Budak | 1986 |
| Mehmet Ali Kuru | Investigations on freshwater gastropods observed in Izmir and its surroundings | Prof. Dr. M. Ali Özcel | 1986 |
| Zuhal Balım | Characteristics of cell types in acute leukemias using different staining methods | Doç. Dr. Nejat Topçuoğlu | 1986 |
| Nuray Altıntaş | Skin dermatoglyphics in diabetes mellitus | Doç. Dr. Cihangir Özkınay | 1986 |
| Serap Avcı | Applications of microspectrophotometry in biology and medicine | Doç. Dr. Nejat Topçuoğlu | 1987 |
| Hüseyin Üzgün | Applications of microphotography methods in medicine and biology | Doç. Dr. Nejat Topçuoğlu | 1988 |
| Nuray Kandemir | Tissue culture techniques in medicine and biology | Doç. Dr. Nejat Topçuoğlu | 1988 |
| Berrin Tuğrul | Investigation of the effects of perlite dust on mouse alveolar macrophages in vitro | Prof. Dr. Nejat Topçuoğlu | 1992 |
| İbrahim Cirit | Investigation of cytological characteristics in ovarian tumors using Epon-812 embedding, one-micron sections and different staining methods | Prof. Dr. Nejat Topçuoğlu | 1993 |
| Buket Kosova | Millipore filtration technique and its use in cytological materials | Prof. Dr. Nejat Topçuoğlu | 1994 |
| Mehmet Kösem | Comparison of cytogenetic diagnostic methods in cases of Fragile X syndrome | Doç. Dr. Ferda Özkınay | 1994 |
| Murat Seleker | Structure, characteristics and medical applications of the micromanipulator | Prof. Dr. Nejat Topçuoğlu | 1995 |
| Vildan Bozok Çetintaş | Investigation of N-acetyltransferase 2 polymorphisms in patients receiving tuberculosis treatment | Yrd. Doç. Dr. Zuhal Eroğlu | 2004 |
| Çığır Biray | Evaluation of the cytotoxic and apoptotic activity of propolis and its active compounds in the human T-cell acute lymphoblastic leukemia cell line CEM-S | Doç. Dr. Cumhur Gündüz | 2004 |
| Burçin Tezcanlı | Investigation of the Val66Met polymorphism in brain-derived neurotrophic factor and the Val108/158Met polymorphism in the catechol-O-methyltransferase gene in psychiatric cases | Yrd. Doç. Dr.Buket Kosova | 2005 |
| Rukiye Özel | Investigation of the I105V polymorphism and promoter-region hypermethylation of the glutathione S-transferase P1 gene in prostate cancer cases | Yrd. Doç. Dr.Buket Kosova | 2006 |
| Zeynep Özlem Doğan | Quantitative determination and evaluation of extracellular plasma DNA in prostate cancer | Doç. Dr. Cumhur Gündüz | 2006 |
| Aslı Tetik | Investigation of the effects of methotrexate-related methylenetetrahydrofolate reductase gene polymorphisms on drug toxicity in patients with rheumatoid arthritis | Yrd. Doç. Dr.Zuhal Eroğlu | 2006 |
| Sunde Yılmaz | Quantitative determination of cytokeratin 20 mRNA expression in bladder cancer by real-time reverse transcriptase polymerase chain reaction | Doç. Dr. Cumhur Gündüz | 2006 |
| Elif Ağatekin | Investigation of the effects of beta-1 adrenergic receptor, beta-2 adrenergic receptor and Gs-protein gene polymorphisms in cases with mitral valve prolapse | Yrd. Doç. Dr. Zuhal Eroğlu | 2007 |
| Özkan Gübe | Effect of the CRP 1059 G/C polymorphism on thrombosis and cardiovascular diseases | Yrd. Doç. Dr. . Zuhal Eroğlu | 2007 |
| Ali Şahin Küçükaslan | Effect of methionine synthase A2756G and methionine synthase reductase A66G gene polymorphisms in male infertility | Yrd. Doç. Dr. Zuhal Eroğlu | 2008 |
| Duygu Döndü Aygüneş | Retrospective evaluation of CES1 gene polymorphism frequencies in patients with metastatic breast cancer and their effects on drug response in capecitabine users | Yrd. Doç. Dr. Buket Kosova | 2008 |
| Ayşegül Dalmızrak | Functional analysis of the role of the TANK protein in signal transduction | Yrd. Doç. Dr. Buket Kosova | 2008 |
| Sinem Numanoğlu | Investigation of the combined effect of genistein and hyperthermia in estrogen-dependent breast cancer cells (MCF-7) | Doç. Dr. Cumhur Gündüz | 2008 |
| Çağdaş Aktan | Significance of cytochrome P450 2B6 (CYP2B6) K262R, Q172H and R378X gene polymorphisms in prostate cancer development | Yrd. Doç. Dr. Buket Kosova | 2008 |
| Müsteyde Yücebaş | Investigation of repressor element-1 silencing transcription factor and repressor element-1 silencing transcription cofactor genes in anaplastic brain tumors | Doç. Dr. Cumhur Gündüz | 2010 |
| Ezgi İnanpolat | Investigation of mutations in the actin-binding region of beta-myosin heavy chain in patients with hypertrophic cardiomyopathy | Yrd. Doç. Dr. Buket Kosova | 2010 |
| Sevcan Atay | Significance of urinary matrix metalloproteinase-2 and matrix metalloproteinase-9 in kidney cancer | Doç. Dr. Zuhal Eroğlu | 2011 |
| Tuğçe Balcı | Microarray transcriptome analysis in leukemia models after non-viral transfection of downregulated miRNAs in leukemogenesis into leukemia cells via polyethylene glycol-polyethylenimine nanoparticles | Prof. Dr. Cumhur Gündüz | 2012 |
| Çağla Kayabaşı | Genome-level investigation of the effects of selected drugs used in chronic myeloid leukemia treatment on leukemia stem cells | Prof. Dr. Cumhur Gündüz | 2012 |
| Zeynep Mutlu | Sequencing of the serine/threonine kinase domain of the bone morphogenetic protein receptor type 2 gene causing pulmonary arterial hypertension | Doç. Dr. Zuhal Eroğlu | 2012 |
| Selin Yeşil | Investigation of single nucleotide polymorphisms at five different loci on the X chromosome by minisequencing | Doç. Dr. Zuhal Eroğlu | 2013 |
| Mertkaya Aras | Therapeutic effect of fucoidan on androgen-sensitive and androgen-insensitive prostate cancer cell lines | Doç. Dr. Buket Kosova | 2013 |
| Cansu Çalışkan | Investigation of the effects of temsirolimus and zoledronic acid combination on apoptosis and miRNA expression changes in glioblastoma | Doç. Dr. Çığır Biray Avcı | 2014 |
| Sezgi Kıpçak | Determination of apoptosis and expression changes in cell-cycle genes in bendamustine-induced HL60 cells | Yrd. Doç. Dr. Nur Selvi Günel | 2014 |
| Bakiye Göker | Investigation of molecular biological changes induced by in vitro application of ruxolitinib in chronic myeloid leukemia treatment | Doç. Dr. Çığır Biray Avcı | 2014 |
| Metin Çalışkan | Investigation of EGFR, KRAS, BRAF, PIK3CA, HER2 and NRAS gene mutations in paraffin block sections from patients diagnosed with non-small cell lung cancer | Yrd. Doç. Dr. Nur Selvi Günel | 2015 |
| Buket Özel | Evaluation of the effects of dasatinib on enzyme activity and protein expression of PP2A catalytic and regulatory subunits in dasatinib-treated K562 cells | Yrd. Doç. Dr. Nur Selvi Günel | 2015 |
| Özgün Özalp | Molecular investigation of the role of temozolomide and vismodegib combination in brain tumor pathogenesis | Doç. Dr. Çığır Biray Avcı | 2015 |
| Ceren Erdem | Effect and significance of circulating miR-223 in cholesterol homeostasis and development of hypercholesterolemia | Doç. Dr. Zuhal Eroğlu | 2017 |
| Fatma Dogan | Molecular biological investigation of the effects of the telomerase inhibitor BIBR1532 in breast cancer and breast cancer stem cells | Doç. Dr. Çığır Biray Avcı | 2017 |
| Fatma Sögütlü | Effect of ICRT-3 on the WNT signaling pathway in head and neck cancer | Prof. Dr. Cumhur Gündüz | 2017 |
| Eda Doğan | Investigation of the effect of epidermal growth factor receptor inhibition on claudins in lung cancer cell lines | Doç. Dr. Vildan Bozok Çetintaş | 2018 |
| Nihal Birden | Effects of the epigallocatechin-3-gallate and dabrafenib combination on apoptosis and gene expression in anaplastic thyroid cancer cells | Dr. Öğr. Üye. Nur Selvi Günel, Doç. Dr. Çığır Biray Avcı | 2019 |
| Yiğit Sezgin | Investigation of the effects of ARHGAP42 rs633185 gene polymorphism on blood pressure and arterial stiffness in hypertensive cases | Doç. Dr. Buket Kosova | 2019 |
| Çağlar Çalebi | Investigation of the effects of the DZNep and stauprimide combination on MYC gene expression in breast cancer | Prof. Dr. Cumhur Gündüz, Yrd. Doç. Dr. Tuğçe Balcı Okcanoğlu | 2019 |
| Alican Kuşoğlu | Molecular effects of BIBR1532 on epithelial-mesenchymal transition in breast cancer and breast cancer stem cells | Doç. Dr. Çığır Biray Avcı | 2012 |
| Selin Çeşmeli | Effect of the BIBR1532 and resveratrol combination on lncRNA expression changes in colorectal cancer cells | Doç. Dr. Çığır Biray Avcı | 2019 |
| Buşra Bara | Effect of resveratrol on telomerase activity associated with NF-kB and hTERT expression in the PANC-1 cell line | Doç. Dr. Fatma Zuhal Eroğlu | 2020 |
| Eda Tayfur | Expression analysis of long non-coding RNAs in patients with type 2 diabetes mellitus and cognitive dysfunction | Prof. Dr. Cumhur Gündüz | 2020 |
| İlayda Alçıtepe | Investigation of the therapeutic effects of the epigenetic agents bromodomain inhibitor PLX51107 and HDAC inhibitor SAHA on an AML cell line | Doç. Dr. Burçin Kaymaz | 2021 |
| Zafer Yıldırım | Investigation of the effects of PTEN mutations and the cGAS/STING pathway on temozolomide response in glioblastoma cells | Doç. Dr. Vildan Bozok Çetintaş | 2021 |
| İlknur Karatekin | Investigation of the therapeutic effects of asciminib (ABL001) and tivantinib (ARQ197) on leukemic and hematopoietic stem cells | Doç. Dr. Burçin Kaymaz | 2021 |
| Ecem Türkmen | Investigation of the anticancer efficacy of telomerase inhibition by BIBR1532 in an anaplastic thyroid cancer cell line | Doç. Dr. Çığır Biray Avcı | 2022 |
| Buse Fındıklı | Effects of resveratrol on cell cycles and NF-kB activation in cisplatin-resistant and parental A2780 cell lines | Doç. Dr. Fatma Zuhal Eroğlu | 2022 |
| Burcu Bölük | Determination of gene mutations in myeloproliferative neoplasms by sequence analysis | Doç. Dr. Sunde Yılmaz Süslüer | 2022 |
| Zeynep Özileri | Investigation of the anticancer effects of glutaminolysis and glycolysis inhibition in a breast cancer cell model | Prof. Dr. Cumhur Gündüz | 2022 |
| Uygar Geniş | Investigation of differential expression profiles of NFAT gene family members in patients with suspected glomerulonephritis | Doç. Dr. Buket Kosova | 2022 |
| Pınar Güler | Effect of the telomerase inhibitor BIBR1532 on the Wnt signaling pathway in breast cancer and breast cancer stem cells | Doç. Dr. Çığır Biray Avcı | 2022 |
| Ayşe Çekin | Cytotoxic and apoptotic effects of propolis and 5-FU combination in HCT-116 colon cancer cells | Doç. Dr. Nur Selvi Günel | 2023 |
| Ayshan Gulmalıyeva | Effects of boron mineral on apoptosis and gene expression in OVCAR-3 ovarian cancer cells | Doç. Dr. Nur Selvi Günel | 2023 |
| Boubacar Balde | Investigation of the effects of epigenetic agents on epithelial-mesenchymal transition transcription factors in acute myeloid leukemia | Doç. Dr. Burçin Kaymaz | 2023 |
| Sevim Aydemir | Investigation of autophagic STING regulation in cisplatin response in lung cancer cell lines | Doç. Dr. Vildan Bozok Çetintaş | 2023 |
| Hilal Başyeğit | Investigation of long non-coding RNAs that may be used as prognostic biomarkers in hepatitis B patients | Doç. Dr. Sunde Yılmaz Süslüer | 2023 |
| Bilge Şenyüz | Investigation of the effects of Fusobacterium nucleatum burden on tumor necrosis factor-alpha therapy in ulcerative colitis | Doç. Dr. Sunde Yılmaz Süslüer | 2023 |
| İrem Karacan | Determination of the effects of selinexor and docetaxel, alone and in combination, on breast cancer cell lines | Doç. Dr. Buket Kosova | 2023 |
| Gizem Akyol | Effects of the STING R232/H232 variant on the prognosis of inflammatory bowel disease | Doç. Dr. Vildan Bozok Çetintaş, Doç. Dr. Miray Karakoyun | 2023 |
| Cansu Çankaya | Investigation of the effects of resveratrol on GRP78 in a cisplatin-resistant Calu-1 lung cancer cell line | Doç. Dr. Fatma Zuhal Eroğlu | 2023 |
| Yasemen Karan Başaran | Effects of the BIBR1532 and resveratrol combination on the WNT signaling pathway in colorectal cancer cells | Doç. Dr. Çığır Biray Avcı | 2023 |
| Umut Soyatlar | Investigation of the anti-inflammatory effect of the natural antioxidant 5,7-dihydroxychromone on a human microglia cell line | Prof. Dr. Cumhur Gündüz | 2024 |
| Emir Çakar | Relationship of the MAN2A1 gene with neuroplasticity in schizophrenia | Doç. Dr. Buket Kosova | 2024 |
| Kutay Bulut | Investigation of potential genetic mechanisms in paroxysmal nocturnal hemoglobinuria | Doç. Dr. Sunde Yılmaz Süslüer | 2024 |
| Hülya Çinar | Investigation of the antiproliferative activity of the synthetic cannabinoid agent JWH-073 in tyrosine kinase inhibitor-sensitive and -resistant cell lines | Doç. Dr. Burçin Kaymaz | 2024 |
| Besne Çelik | Investigation of the therapeutic effects of CRISPR/Cas9-mediated STAT5A knockout in tyrosine kinase inhibitor-resistant chronic myeloid leukemia cells | Doç. Dr. Burçin Kaymaz | 2024 |
| Emine Dursiye Çalışkan | Investigation of telomere length in patients with neuromyelitis optica spectrum disorder (NMOSD) | Doç. Dr. Nur Selvi Günel | 2025 |
| Zeynep Gaye Hamarat | Synthesis, characterization and cytotoxicity analyses of zinc oxide nanoparticle-integrated polymeric hydrogel | Doç. Dr. Nur Selvi Günel | 2025 |
| Dilay Gül KAPUSUZ | Investigation of the effects of TBK1 inhibitors on inflammatory responses in lymphocytes from patients diagnosed with inflammatory bowel disease | Prof. Dr. Vildan Bozok | 2026 |
| Selma Ferda DALAR | Determination of specific circRNA expression levels in advanced-stage non-small cell lung cancer | Prof. Dr. Aslı Tetik Vardarlı | 2026 |
| Arman ROSTAMLOU | Role of lncRNA LUCAT1 in microglia-activating signaling pathways and its effect on glioblastoma cells through microglia | Prof. Dr. Cumhur Gündüz | 2026 |
| Sude TINAZ | Integrated genomic and clinicopathological analysis of somatic variants in lung cancer by next-generation sequencing | Prof. Dr. Cumhur Gündüz | 2026 |
| Uzay AÇIKGÖZ | Effect of temozolomide-propolis combination on miRNAs in glioblastoma cell lines | Prof. Dr. EMİN KARACA | 2026 |
